Kiko Garcia

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Microbiome Profiling by Sequencing: Definitions and Technologies | #amplicon based next-generation sequencing

Microbiome Profiling by Sequencing: Definitions and Technologies

Microbiome Profiling by Sequencing: Definitions and Technologies

The sequencing technologies offer solutions for precise identification of microorganisms as well as interpretation of how they interact within the microbiome and with the environment.

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Targeting RNA Splicing: Mechanisms and Strategies | #alternative Splicing

Targeting RNA Splicing: Mechanisms and Strategies

Targeting RNA Splicing: Mechanisms and Strategies

RNA splicing is a post-transcriptional modification process that occurs in eukaryotic cells. When a gene is transcribed, the initial RNA product is called pre-mRNA, which contains both coding regions (exons) and non-coding regions (introns). RNA splicing removes the introns from the pre-mR

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Decoding the Role of Chimeric RNA in Cellular Processes | #rna Sequencing

Decoding the Role of Chimeric RNA in Cellular Processes

Decoding the Role of Chimeric RNA in Cellular Processes

Chimeric RNA, also known as fusion RNA, refers to RNA molecules that are formed as a result of the fusion of two or more different RNA transcripts. Chimeric RNA, a unique class of RNA molecules formed through various molecular mechanisms, such as trans-splicing, read-through transcription,

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A Comparative Analysis of Prime Editing and CRISPR-Cas9 | #crispr-Cas9

A Comparative Analysis of Prime Editing and CRISPR-Cas9

A Comparative Analysis of Prime Editing and CRISPR-Cas9

CRISPR-Cas9 uses a two-component system consisting of a guide RNA (gRNA) and a Cas9 protein. The gRNA is designed to complement specific target sequences in the genome to guide the Cas9 protein to the desired location.

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Variant Analysis Workflow in Bioinformatics | #variant Analysis

Variant Analysis Workflow in Bioinformatics

Variant Analysis Workflow in Bioinformatics

Rare DNA changes within a population of cells are the first manifestations of mutations, which are the fuel for evolution. The research of genomic variation between species and individual organisms has been revolutionized by next-generation sequencing (NGS) technologies.

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